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The herbicide 2,4-dichlorophenoxyacetic acid induces pancreatic β-cell death via oxidative stress-activated AMPKα signal downstream-regulated apoptotic pathway

Ken-An Lin, Chin‐Chuan Su, Kuan-I Lee, Shing‐Hwa Liu, Kai‐Min Fang, Choon‐Hong Tan, Wei-Cheng Lia, Chun-Ying Kuo, Kai‐Chih Chang, Chun-Fa Huang, Ya-Wen Chen, Ching‐Yao Yang

2025Toxicology Letters12 citationsDOI

Topics & Concepts

AMPKApoptosis2,4-Dichlorophenoxyacetic acidCell biologyOxidative stressChemistryDownstream (manufacturing)Programmed cell deathBiologyBiochemistryBotanyPhosphorylationProtein kinase AOperations managementEconomicsPancreatic function and diabetesMetabolism, Diabetes, and CancerCalcium signaling and nucleotide metabolism
The herbicide 2,4-dichlorophenoxyacetic acid induces pancreatic β-cell death via oxidative stress-activated AMPKα signal downstream-regulated apoptotic pathway | Litcius