Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells
Xingying Zhang, Chenze Zhang, Miaomiao Qiao, Chen Cheng, Na Tang, Shan Lu, Wen Sun, Beilei Xu, Yuanwei Cao, Xiaofei Wei, Yao Wang, Weidong Han, Haoyi Wang
Topics & Concepts
Transcription factorBiologyCancer researchEffectorChimeric antigen receptorCell growthCell biologyCellT cellImmunologyGeneGeneticsImmune systemCAR-T cell therapy researchImmune Cell Function and InteractionViral Infectious Diseases and Gene Expression in Insects