Hydrogen-bonded supramolecular polymer micelles with pH/photothermal-responsive carmofur release and combined chemo-photothermal therapy
Yanggui Wu, Huiying Wang, Qianqian Liu, Frédéric Lortie, Julien Bernard, Wolfgang H. Binder, Senbin Chen, Jintao Zhu
Abstract
This work targets the construction of hydrogen-bonded (H-bonded) supramolecular polymeric micelles loaded with chemotherapy drugs (carmofur) and photothermal agents (IR780) for combined chemo-photothermal therapies (CT/PTT).
Topics & Concepts
Photothermal therapyMicelleSupramolecular chemistryPolymerChemistryPhotothermal effectMaterials scienceNanotechnologyOrganic chemistryMoleculeAqueous solutionSupramolecular Self-Assembly in MaterialsNanoplatforms for cancer theranosticsMetal-Organic Frameworks: Synthesis and Applications