Nanoarchitectonics of Cartilage-Targeting Hydrogel Microspheres with Reactive Oxygen Species Responsiveness for the Repair of Osteoarthritis
Yu Han, Chenglong Huang, Xiangjia Kong, Jun Ma, Peng Ren, Jiayi Chen, Xinyu Zhang, Huanhuan Luo, Gang Chen
Abstract
. Additionally, the hydrogel microspheres, similar to bees, could target and effectively repair cartilage in the OA model. Thus, the injectable hydrogel microspheres exerted an excellent potential to repair OA and may also provide an effective avenue for inflammatory bowel disease therapy.
Topics & Concepts
Reactive oxygen speciesChondrogenesisMaterials scienceCartilageSelf-healing hydrogelsOsteoarthritisNanotechnologyBiophysicsBiomedical engineeringCell biologyMedicinePathologyBiologyAnatomyAlternative medicinePolymer chemistryOsteoarthritis Treatment and MechanismsTendon Structure and TreatmentKnee injuries and reconstruction techniques