Functional Thermoresponsive Hydrogel Molecule to Material Design for Biomedical Applications
Sagar R. Pardeshi, Fouad Damiri, Mehrukh Zehravi, Rohit Joshi, Harshad S. Kapare, Mahendra Prajapati, Neha Munot, Mohammed Berrada, Prabhanjan Giram, Satish Rojekar, Faraat Ali, Md. Habibur Rahman, Hasi Rani Barai
Abstract
Temperature-induced, rapid changes in the viscosity and reproducible 3-D structure formation makes thermos-sensitive hydrogels an ideal delivery system to act as a cell scaffold or a drug reservoir. Moreover, the hydrogels' minimum invasiveness, high biocompatibility, and facile elimination from the body have gathered a lot of attention from researchers. This review article attempts to present a complete picture of the exhaustive arena, including the synthesis, mechanism, and biomedical applications of thermosensitive hydrogels. A special section on intellectual property and marketed products tries to shed some light on the commercial potential of thermosensitive hydrogels.