Targeted protein degradation: Emerging concepts and protein state-specific targeting principles
Andrew J. Tao, Gillian E. Gadbois, Stanley A. Buczynski, Fleur M. Ferguson
Topics & Concepts
Ubiquitin ligaseProtein degradationSmall moleculeTarget proteinUbiquitinChemical biologyComputational biologyDrug discoveryCell biologyLigand (biochemistry)Chemical geneticsTernary complexBiologyChemistryBiochemistryEnzymeReceptorGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis