ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer
Jackson Liang, Xiaosai Yao, Patrick Aouad, Bu-Er Wang, Lisa Crocker, Subhra Chaudhuri, Yuxin Liang, Spyros Darmanis, Jennifer M. Giltnane, Heather M. Moore, Junko Aimi, Ching‐Wei Chang, Mary Gates, Jennifer Eng‐Wong, Marc Hafner, Ciara Metcalfe
Topics & Concepts
Breast cancerLineage (genetic)Cancer researchPlasticityOncologyMedicineCancerInternal medicineBiologyGeneticsGenePhysicsThermodynamicsBRCA gene mutations in cancerGenomics and Chromatin DynamicsCancer-related Molecular Pathways