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Optimization of activity localization of quinoline derivatives: Design, synthesis, and dual evaluation of biological activity for potential antitumor and antibacterial agents

Guofan Jin, Zhenwang Li, Fuyan Xiao, Xueyong Qi, Xian‐Yu Sun

2020Bioorganic Chemistry38 citationsDOI

Topics & Concepts

ChemistryHeLaEscherichia coliAntibacterial activityCytotoxicityAmine gas treatingStaphylococcus aureusMinimum inhibitory concentrationStereochemistryProton NMRQuinolineNuclear chemistryIn vitroBacteriaBiochemistryOrganic chemistryGeneticsGeneBiologySynthesis and biological activitySynthesis and Biological EvaluationCancer therapeutics and mechanisms
Optimization of activity localization of quinoline derivatives: Design, synthesis, and dual evaluation of biological activity for potential antitumor and antibacterial agents | Litcius