Facile synthesis of a cyclodextrin-metal organic framework decorated with Ketjen Black and platinum nanoparticles and its application in the electrochemical detection of ofloxacin
Feng Luan, Yunfei Wang, Shuang Zhang, Xuming Zhuang, Chunyuan Tian, Xiuli Fu, Lingxin Chen
Abstract
A facile and novel method was developed to improve the conductivity of a cyclodextrin-metal organic frameworks (CD-MOFs) by modifying it with Ketjen Black (KB) and platinum nanoparticles (PtNPs). The structural morphology and composition of this PtNPs/KB/CD-MOFs nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, elemental mapping, and Raman spectroscopy. The sensor was then evaluated for its ability to detect ofloxacin using cyclic voltammetry, and the results showed that the PtNPs/KB/CD-MOF had high sensitivity, satisfactory stability and good reproducibility. In addition, a great linear range was obtained with a concentration range of 0.08-100 μM and a low detection limit of 0.037 μM (S/N = 3). Therefore, the prepared electrochemical sensor could be successfully used to detect ofloxacin in serum.