The combined disulfide cross-linking and tyrosine-modification of very low molecular weight linear PEI synergistically enhances transfection efficacies and improves biocompatibility
Michael Karimov, Dietmar Appelhans, Alexander Ewe, Achim Aigner
Topics & Concepts
BiocompatibilityTransfectionPolyethylenimineGene deliveryChemistryCytotoxicitySmall moleculeDrug deliveryNucleic acidBiochemistryBiophysicsCombinatorial chemistryIn vitroBiologyOrganic chemistryGeneRNA Interference and Gene DeliveryVirus-based gene therapy researchAdvanced biosensing and bioanalysis techniques