Persistent glutathione-depleting MFO@MIL nanoreactors enhance the antitumor efficiency of a skin scaffold
Wenjing Yang, Yibing Ji, Lang Li, Chenhang Ding, Wurikaixi Aiyiti, Feilong Xiong, Cijun Shuai
Abstract
The efficacy of reactive oxygen species (ROS)-related skin tumor therapies is significantly restricted by intracellular overexpressed glutathione (GSH) which is a free radical scavenger.
Topics & Concepts
ScaffoldNanoreactorGlutathioneMaterials scienceNanotechnologyChemistryBiomedical engineeringMedicineBiochemistryEnzymeNanoparticleGraphene and Nanomaterials ApplicationsNanoplatforms for cancer theranosticsSupramolecular Self-Assembly in Materials