Copper-catalyzed asymmetric allylic substitution of racemic/<i>meso</i> substrates
Jun Li, Junrong Huang, Yan Wang, Yuexin Liu, Yuxiang Zhu, Hengzhi You, Fen‐Er Chen
Abstract
This review focuses on the advancements in Cu-catalyzed asymmetric allylic substitution using racemic/ meso substrates, detailing the ligands used, the scope of nucleophiles, the underlying dynamic processes, and their practical applications.
Topics & Concepts
Allylic rearrangementSubstitution (logic)CatalysisCopperChemistrySubstitution reactionCombinatorial chemistryMedicinal chemistryOrganic chemistryComputer scienceProgramming languageAsymmetric Synthesis and CatalysisChemical Synthesis and AnalysisChemical synthesis and alkaloids