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Role of <i>de novo</i> cholesterol synthesis enzymes in cancer

Jie Yang, Lihua Wang, Renbing Jia

2020Journal of Cancer62 citationsDOIOpen Access PDF

Abstract

cholesterol synthesis pathway to tumorigenesis, cancer progression and metastasis. In conclusion, cholesterol metabolism could be an effective target for novel anticancer treatment.

Topics & Concepts

CancerLipid metabolismCarcinogenesisMetastasisCholesterolCancer cellCancer researchCholesterol synthesisEnzymeMedicineMetabolismBioinformaticsBiologyBiochemistryInternal medicineReductaseCancer, Lipids, and MetabolismCholesterol and Lipid MetabolismPeroxisome Proliferator-Activated Receptors
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