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The Imperfect Cytokine Storm

Vinh Q. Chau, Estefanía Oliveros, Kiran Mahmood, Aditi Singhvi, Anuradha Lala, Noah Moss, Umesh Gidwani, Donna Mancini, Sean Pinney, Aditya Parikh

2020JACC Case Reports74 citationsDOIOpen Access PDF

Abstract

As health systems worldwide grapple with the coronavirus disease-2019 (COVID-19) pandemic, patients with durable LVAD support represent a unique population at risk for the disease. This paper outlines the case of such a patient who developed COVID-19 complicated by a "cytokine storm" with severe acute respiratory distress syndrome and myocardial injury and describes the challenges that arose during management.

Topics & Concepts

Cytokine stormCoronavirus disease 2019 (COVID-19)Acute respiratory distressPandemicIntensive care medicineStormMedicineImperfectPopulationDiseaseCoronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cytokine release syndrome2019-20 coronavirus outbreakCytokineInfectious disease (medical specialty)ImmunologyVirologyInternal medicineGeographyEnvironmental healthLungMeteorologyLinguisticsPhilosophyOutbreakRespiratory Support and MechanismsLong-Term Effects of COVID-19COVID-19 Clinical Research Studies
The Imperfect Cytokine Storm | Litcius