Endothelial calcium firing mediates the extravasation of metastatic tumor cells
Marina Peralta, Amandine Dupas, Annabel Larnicol, Olivier Lefèbvre, Ruchi Goswami, Tristan Stemmelen, Anne Molitor, Raphaël Carapito, Salvatore Girardo, Naël Osmani, Jacky G. Goetz
Abstract
channels as key mediators of the process. These results further highlight the central role of endothelial remodeling during the extravasation of TCs and open avenues for successful therapeutic targeting.
Topics & Concepts
ExtravasationCalciumChemistryBiophysicsCancer researchTumor cellsMedicinePathologyBiologyInternal medicineErythrocyte Function and PathophysiologyVenomous Animal Envenomation and StudiesCell death mechanisms and regulation