Knockdown of miRNA-134-5p rescues dendritic deficits by promoting AMPK-mediated mitophagy in a mouse model of depression
Guoli Wang, Ying Liu, Xue‐Jie Zhu, Kehao Lin, Mingkai Li, Zhenke Wu, Ronghua Zhang, Qiusheng Zheng, Defang Li, Tianyue An
Topics & Concepts
MitophagyAutophagyAMPKGene knockdownDendritic spineCell biologyMitochondrionHippocampal formationHippocampusNeurogenesisNeuroscienceBiologyPINK1Protein kinase AChemistryKinaseBiochemistryApoptosisAutophagy in Disease and TherapyMicroRNA in disease regulationNeurogenesis and neuroplasticity mechanisms