Multi-stage screening to predict the specific anticancer activity of Ni(II) mixed-ligand complex on gastric cancer cells; biological activity, FTIR spectrum, DNA binding behavior and simulation studies
Leily Heidarpoor Saremi, Karim Dadashi Noshahr, Ali Ebrahimi, Ali Khalegian, Khatereh Abdi, Milad Lagzian
Topics & Concepts
ChemistryDNAAmideCovalent bondFourier transform infrared spectroscopyMTT assayNucleic acidLigand (biochemistry)StereochemistryIn vitroBiochemistryOrganic chemistryReceptorPhysicsQuantum mechanicsMetal complexes synthesis and propertiesComputational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds