Nephroprotective effects of hesperidin on ifosfamide-induced acute nephrotoxicity in rats: Role of NF-κB/TNF-α/ IL-1β, p53/caspase-3/Bax/Bcl-2, and ATF6/IRE1/PERK/GRP78 signaling pathways
Özge Kandemir, Nurhan Akaras, Hasan Şimşek, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Cüneyt Çağlayan, Fatih Mehmet Kandemır
Topics & Concepts
HesperidinApoptosisNephrotoxicityPharmacologySignal transductionTumor necrosis factor alphaNF-κBCaspaseUnfolded protein responseCaspase 3MedicineChemistryCancer researchImmunologyProgrammed cell deathInternal medicineKidneyBiochemistryPathologyAlternative medicineChemotherapy-induced organ toxicity mitigationAluminum toxicity and tolerance in plants and animalsGenomics, phytochemicals, and oxidative stress