Ferrous Iron Uptake Is Required for Salmonella to Persist within Vacuoles of Host Cells
Lorena Domínguez-Acuña, Francisco Garcı́a-del Portillo
Abstract
Iron is an essential oligoelement that incorporates into proteins as a biocatalyst or electron carrier. The intracellular pathogen Salmonella enterica serovar Typhimurium ( S. Typhimurium) takes iron as free reduced ferrous cation or as oxidized ferric cation complexed to siderophores or ferrichromes.
Topics & Concepts
VacuoleFerrousSalmonella entericaBiologyVirulenceIntracellularMicrobiologySiderophoreSalmonellaIntracellular parasiteBacteriaFerricBiochemistryPathogenChemistryCytoplasmGeneGeneticsOrganic chemistryIron Metabolism and DisordersTrace Elements in HealthSalmonella and Campylobacter epidemiology