Associations between oxygen delivery and cardiac index with hyperlactatemia during cardiopulmonary bypass
Ignazio Condello, Giuseppe Santarpino, Giuseppe Nasso, Marco Moscarelli, Flavio Fiore, Giuseppe Speziale
Abstract
OBJECTIVE: ). METHODS: 75% was used. During CPB, serial arterial blood gas analyses with blood lactate and glucose determinations were obtained. Hyperlactatemia (HL) was defined as a peak arterial blood lactate concentration >3 mmol/L. The postoperative outcome of patients with or without HL was compared. RESULTS: >75% in group B were found to have a negative predictive value of 78% and 62% for HL, respectively. CONCLUSIONS: . Group A reported a significant reduction in the incidence of intraoperative lactate peak, correlated with postoperative reduction of serum creatinine value, mechanical ventilation time, and intensive care unit stay, compared with group B.