USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A
Mingchao Mu, Qin Zhang, Jing Li, Chenye Zhao, Xiaopeng Li, Zilu Chen, Xuejun Sun, Junhui Yu
Topics & Concepts
HIF1AColorectal cancerUbiquitin ligaseSUMO proteinCancer researchBiologyOncogeneHypoxia (environmental)CancerCell biologyUbiquitinChemistryAngiogenesisGeneticsGeneCell cycleOrganic chemistryOxygenCancer, Hypoxia, and MetabolismUbiquitin and proteasome pathwaysCancer-related Molecular Pathways