Litcius/Paper detail

Persistent spectral theory-guided protein engineering

Yuchi Qiu, Guo‐Wei Wei

2023Nature Computational Science58 citationsDOIOpen Access PDF

Topics & Concepts

Protein designComputer scienceProtein engineeringSequence spaceProtein structure predictionPersistent homologyTopology (electrical circuits)Fitness landscapeProtein sequencingInvariant (physics)Artificial intelligenceProtein structureMathematicsAlgorithmPeptide sequenceBiologyGeneticsDiscrete mathematicsCombinatoricsDemographyBiochemistryMathematical physicsPopulationGeneEnzymeBanach spaceSociologyBioinformatics and Genomic NetworksHIV Research and TreatmentTopological and Geometric Data Analysis