A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors
Haseen Ahmad, Faisal Ahmad, Shaista Parveen, Sajjad Ahmad, Syed Sikander Azam, Abbas Hassan
Topics & Concepts
ChemistryThiazoleCombinatorial chemistryDocking (animal)BromideStereochemistryArylActive siteCatalysisAntimicrobialPiperidineOrganic chemistryAlkylMedicineNursingClick Chemistry and ApplicationsSynthesis and Catalytic ReactionsChemical Synthesis and Analysis