Continuous-flow reductive <i>N</i>-methylation with highly active heterogeneous Pd catalysts and sequential-flow synthesis of <i>N</i>-monomethyl amines
Yuki Saito, Taisei Senzaki, Ken Nishizawa, Shū Kobayashi
Abstract
We describe continuous-flow N -methylation with formaldehyde and H 2 using heterogeneous Pd catalysts as a green synthetic method to access N -methyl amines.
Topics & Concepts
CatalysisChemistryFlow (mathematics)Combinatorial chemistryContinuous flowFlow chemistryMethylationOrganic chemistryBiochemistryMathematicsBiochemical engineeringGeometryGeneEngineeringAsymmetric Hydrogenation and CatalysisNanomaterials for catalytic reactionsInnovative Microfluidic and Catalytic Techniques Innovation