Single-Cell Transcriptome Atlas of Newcastle Disease Virus in Chickens Both <i>In Vitro</i> and <i>In Vivo</i>
Weiwei Liu, Zejun Xu, Yafeng Qiu, Xusheng Qiu, Lei Tan, Cuiping Song, Yingjie Sun, Ying Liao, Xiufan Liu, Chan Ding
Abstract
Newcastle disease virus (NDV) is an avian paramyxovirus that causes major economic losses to the poultry industry around the world, with NDV pathogenicity varying due to strain virulence differences. However, the impacts of intracellular viral replication and the heterogeneity of host responses among cell types are unknown.
Topics & Concepts
Newcastle diseaseTranscriptomeAtlas (anatomy)In vivoVirologyVirusBiologyIn vitroGeneticsGeneGene expressionAnatomyAnimal Virus Infections StudiesVirology and Viral Diseasesinterferon and immune responses