Unraveling the pathogenesis and prevention strategies of acute high-altitude illness through gut microecology
Ping Qi, Xiansen Jiang, Xiaojuan Wang, Liang Sheng, Jiawen Liang, Lei Zhang
Abstract
High-altitude environments, characterized by hypobaric and hypoxic conditions, induce acute hypoxia, resulting in decreased blood oxygen saturation. This hypoxic stress perturbs gut microecological homeostasis, significantly contributing to the pathogenesis of acute mountain sickness. Consequently, elucidating the mechanisms by which high altitude affects gut homeostasis is crucial for developing effective interventions.
Topics & Concepts
MicroecologyPathogenesisMedicineImmunologyBiologyMicrobiologyGut microbiota and healthHigh Altitude and HypoxiaDiet and metabolism studies