Doxorubicin and doxorubicin-loaded nanoliposome induce senescence by enhancing oxidative stress, hepatotoxicity, and in vivo genotoxicity in male Wistar rats
Mohammad Shokrzadeh, Abouzar Bagheri, Nasrin Ghassemi-Barghi, Nazanin Rahmanian, Morteza Eskandani
Topics & Concepts
Oxidative stressDoxorubicinApoptosisSenescencePharmacologyGenotoxicityToxicityIn vivoFlow cytometryAnnexinNecrosisChemistryBiologyMedicinePathologyImmunologyInternal medicineChemotherapyBiochemistryCell biologyBiotechnologyNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsCell death mechanisms and regulation