NPR3, transcriptionally regulated by POU2F1, inhibits osteosarcoma cell growth through blocking the PI3K/AKT pathway
Shuo Li, Ruirong Guo, Zhibin Peng, Bingxuan Quan, Yuhang Hu, Yiwen Wang, Yiwen Wang, Yansong Wang, Yansong Wang
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayCell growthTranscription factorBiologyCancer researchDownregulation and upregulationGene knockdownSignal transductionGene silencingCell cultureApoptosisCell biologyBiochemistryGeneGeneticsPeptidase Inhibition and AnalysisHeart Failure Treatment and ManagementCancer-related gene regulation