sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway
Yuehuai Hu, Jie Liu, Jing Lü, Panxia Wang, Jianxing Chen, Ying Guo, Fanghai Han, Junjian Wang, Wěi Li, Peiqing Liu
Topics & Concepts
Wnt signaling pathwayCardiotoxicityDoxorubicinPharmacologyApoptosisLRP6Viability assayFrizzledSignal transductionChemistryWNT3ACancer researchCell biologyBiologyMedicineInternal medicineToxicityChemotherapyBiochemistryWnt/β-catenin signaling in development and cancerPeptidase Inhibition and AnalysisChemotherapy-induced cardiotoxicity and mitigation