The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance
Justin L. Engel, Xiao Zhang, Mingming Wu, Yan Wang, Jose Espejo Valle-Inclán, Qing Hu, Kidist S Woldehawariat, Mathijs A. Sanders, Agata Smogorzewska, Jin Chen, Isidro Cortés‐Ciriano, Roger S. Lo, Peter Ly
Topics & Concepts
BiologyFanconi anemiaDrug resistanceCancer researchChromothripsisCancerGeneticsDrugDNADNA repairDNA damagePharmacologyGenome instabilityCRISPR and Genetic EngineeringDNA Repair MechanismsChromosomal and Genetic Variations