Thalidomide Attenuates Colitis and Is Associated with the Suppression of M1 Macrophage Polarization by Targeting the Transcription Factor IRF5
Jiaxi Lu, Deliang Liu, Yuyong Tan, Rong Li, Xuehong Wang, Feihong Deng
Topics & Concepts
IRF5Macrophage polarizationColitisMedicineHepatologyTranscription factorIRF1ImmunologyInternal medicineUlcerative colitisTransplant surgeryInterferon regulatory factorsCancer researchMacrophageImmune systemBiologyInnate immune systemDiseaseGeneBiochemistryIn vitroMultiple Myeloma Research and TreatmentsRheumatoid Arthritis Research and TherapiesImmune cells in cancer