Synthesis of homophthalimide spironaphthalenones through [5 + 1] spiroannulation of aryl/alkenyl enaminones with diazo homophthalimides
Chun Yang, Xinying Zhang, Xuesen Fan
Abstract
Presented herein is a novel synthesis of homophthalimide spironaphthalenones from the cascade reaction of enaminones with diazo homophthalimides.
Topics & Concepts
ChemistryDiazoArylMedicinal chemistryOrganic chemistryAlkylCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions