Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory and analgesic agent
Feng Gao, Ziqi Dai, Tong Zhang, Yuhao Gu, Desheng Cai, Mingjun Lu, Zijie Zhang, Qi Zeng, Bingxian Shang, Bing Xu, Haimin Lei
Abstract
. The results attained in this study indicated that compound 17 had the potential to be developed into an anti-inflammation and analgesic agent.
Topics & Concepts
SinomenineAnti-inflammatoryIn vivoAnalgesicPharmacologyChemistryInflammationCytokineDrugIn vitroIC50MedicineBiochemistryImmunologyBiologyBiotechnologyBerberine and alkaloids researchPiperaceae Chemical and Biological StudiesSynthesis and bioactivity of alkaloids