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CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial

Kim A. Reiss, Mathew G. Angelos, E. Claire Dees, Yuan Yuan, Naoto T. Ueno, Paula R. Pohlmann, Melissa L. Johnson, Joseph Chao, Olga Shestova, Jonathan S. Serody, Maggie Schmierer, Madison Kremp, Michael Ball, Rehman Qureshi, Benjamin H. Schott, Poonam Sonawane, Sabrina Ceeraz DeLong, Melissa Christiano, Ramona F. Swaby, Sascha Abramson, Ken Locke, Débora Barton, Eugene P. Kennedy, Saar Gill, Daniel J. Cushing, Michael Klichinsky, Thomas Condamine, Yara Abdou

2025Nature Medicine192 citationsDOI

Topics & Concepts

MacrophageMedicineCancer researchOncologyInternal medicineBiologyGeneticsIn vitroCAR-T cell therapy researchImmune cells in cancerPhagocytosis and Immune Regulation
CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial | Litcius