A water-soluble thiophene-croconaine dye with a high molar extinction coefficient for NIR fluorescence imaging-guided synergistic photothermal/photodynamic therapy of cancer
E Pang, Rong Huang, Shaojing Zhao, Ke Yang, Baoling Li, Qiuxia Tan, Siyi Tan, Minhuan Lan, Benhua Wang, Xiangzhi Song
Abstract
. Moreover, TCR has a high photothermal conversion efficiency of 77% and is capable of generating hydroxyl radicals (OH˙) under 735 nm laser irradiation. Based on these outstanding properties, TCR has proven its application in NIR fluorescence imaging-guided synergistic photothermal/photodynamic therapy of cancer.
Topics & Concepts
Molar absorptivityPhotothermal therapyFluorescenceThiophenePhotodynamic therapyMaterials scienceExtinction (optical mineralogy)Fluorescence-lifetime imaging microscopyPhotochemistryMolarNanotechnologyChemistryOpticsMineralogyMedicineDentistryOrganic chemistryPhysicsNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisPhotoacoustic and Ultrasonic Imaging