C-C motif chemokine receptor 2 inhibition reduces liver fibrosis by restoring the immune cell landscape
Yangkun Guo, Chong Zhao, Wenting Dai, Bowen Wang, Enjiang Lai, Yang Xiao, Chengwei Tang, Zhiyin Huang, Jinhang Gao
Abstract
inactivating the CCR2-STAT1/NFκB/ERK signaling pathways.
Topics & Concepts
CCR2ChemokineFibrosisCancer researchChemokine receptorMAPK/ERK pathwaySignal transductionBiologyHepatic stellate cellImmunologyCell biologyImmune systemMedicinePathologyEndocrinologyLiver physiology and pathologyLiver Disease Diagnosis and TreatmentLiver Diseases and Immunity