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The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1

Han Han, Hiroki J. Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W. Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang

2022Nature Cell Biology63 citationsDOIOpen Access PDF

Topics & Concepts

Hippo signaling pathwayPhosphorylationCell biologyTranscription factorKinaseEffectorBiologyYAP1GeneBiochemistryHippo pathway signaling and YAP/TAZPhytochemical and Pharmacological Studies
The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1 | Litcius