Litcius/Paper detail

Isoxanthohumol, a component of Sophora flavescens, promotes the activation of the NLRP3 inflammasome and induces idiosyncratic hepatotoxicity

Li Lin, Yuanyuan Chen, Qiang Li, Guang Xu, Kaixin Ding, Lutong Ren, Wei Shi, Yan Wang, Zhiyong Li, Wenzhang Dai, Ziying Wei, Yan Yang, Zhaofang Bai, Xiaohe Xiao

2021Journal of Ethnopharmacology13 citationsDOI

Topics & Concepts

InflammasomeSophora flavescensPharmacologyWestern blotBiochemistryAIM2Molecular biologyChemistryBiologyReceptorMatrineChromatographyGeneInflammasome and immune disordersHops Chemistry and ApplicationsDrug-Induced Hepatotoxicity and Protection