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Percutaneous Thermal Ablation for Early-Stage Breast Cancer: An Open-Label, Randomized, Phase II Trial to Select the Preferred Technique for Evaluating Thermal Ablation as a Surgical Alternative

Sophie M Wooldrik, Elles M.F. van de Voort, Gerson M. Struik, Bart J. M. Schouten, Glenn Yo, Maura Macco, Frank Hulsebosch, Adriaan Moelker, Suzanne Wilhelmus, Renata Sinke, Erwin Birnie, Thijs van Dalen, Cornelis Verhoef, T.M.A.L. Klem

2025Radiology5 citationsDOIOpen Access PDF

Abstract

This phase II study compared radiofrequency ablation, microwave ablation, and cryoablation for early-stage breast cancer, demonstrating that cryoablation achieved the highest complete ablation rate with no complications, supporting its selection for a phase III trial.

Topics & Concepts

MedicineThermal ablationPercutaneousAblationRandomized controlled trialBreast cancerStage (stratigraphy)SurgeryRadiologyCancerInternal medicinePaleontologyBiologyLaser Applications in Dentistry and MedicineAdvanced Radiotherapy TechniquesOptical Imaging and Spectroscopy Techniques
Percutaneous Thermal Ablation for Early-Stage Breast Cancer: An Open-Label, Randomized, Phase II Trial to Select the Preferred Technique for Evaluating Thermal Ablation as a Surgical Alternative | Litcius