Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria
Paul J. Weldrick, Matthew J. Hardman, Vesselin N. Paunov
Abstract
We developed a novel active nanocarrier of common antibiotics, which can efficiently degrade biofilms of resistant bacteria and bypass their defences.
Topics & Concepts
NanocarriersBiofilmBacteriaAntibioticsMicrobiologyProteaseChemistryNanotechnologyMaterials scienceBiologyDrug deliveryBiochemistryEnzymeGeneticsBacterial biofilms and quorum sensingAntimicrobial Peptides and ActivitiesAdvanced Drug Delivery Systems