NH bond activation of ammonia and amines by ditetrelenes: key insights into the stereochemistry of nucleophilic addition
Sarah L. McOnie, Gül Altınbaş Özpınar, Jeremy L. Bourque, Thomas Müller, Kim M. Baines
Abstract
-oriented zwitterionic intermediate, (b) that intermolecular transfer of a proton is not energetically feasible in non-polar solvents, and (c) that the bulk of the substituents can have a profound effect on the stereochemical course of the reaction. With this detailed understanding, nucleophilic additions to ditetrelenes can be exploited in the future.
Topics & Concepts
ChemistryNucleophileAdductAmmoniaIntermolecular forceNucleophilic additionAmine gas treatingProtonHydrolysisReaction mechanismLiquid ammoniaStereochemistryComputational chemistryPhotochemistryMedicinal chemistryOrganic chemistryMoleculeCatalysisPhysicsQuantum mechanicsSynthesis and characterization of novel inorganic/organometallic compoundsOrganoboron and organosilicon chemistryN-Heterocyclic Carbenes in Organic and Inorganic Chemistry