Understanding of chiral site-dependent enantioselective identification on a plasmon-free semiconductor based SERS substrate
Jing Xu, Yuanfei Xue, Xiaoxia Jian, Yue Zhao, Zhenqing Dai, Jingwen Xu, Zhida Gao, Ye Mei, Yan‐Yan Song
Abstract
-DOPA for the onsite growth of Prussian blue (PB), the enantioselectivity difference between l-DOPA and d-DOPA on the homochiral substrate can be directly monitored from PB signals in the Raman-silent region. By combining the experimental results with molecular dynamic (MD) simulations, it is found that satisfactory enantioselective identification not only requires a homochiral surface but also largely depends on the chiral center environment-differentiated hydrogen-bond formation availability.
Topics & Concepts
Enantioselective synthesisSubstrate (aquarium)PlasmonSemiconductorIdentification (biology)Substrate specificityNanotechnologyMaterials scienceChemistryCombinatorial chemistryOptoelectronicsOrganic chemistryCatalysisBiologyEnzymeBotanyEcologyAdvanced biosensing and bioanalysis techniquesGold and Silver Nanoparticles Synthesis and ApplicationsMolecular Sensors and Ion Detection