Structure-guided discovery of tau-phosphorylating kinase DYRK1A inhibitors for therapeutic targeting of neuroinflammatory diseases: Insights from microsecond MD simulation and MMPBSA analyses
Arunabh Choudhury, Sumaiya Khan, Mohammad Umar Saeed, Taj Mohammad, Afzal Hussain, Mohamed F. Alajmi, Urooj Fatima, Asimul Islam, Md. Imtaiyaz Hassan
Topics & Concepts
DYRK1AMicrosecondPhosphorylationKinaseChemistryCancer researchPharmacologyComputational biologyMedicineBiologyBiochemistryPhysicsAstronomy14-3-3 protein interactionsDown syndrome and intellectual disability research