Splice variants of lncRNA RNA ANRIL exert opposing effects on endothelial cell activities associated with coronary artery disease
Hyosuk Cho, Yabo Li, Stephen Archacki, Fan Wang, Gang Yu, Susmita Chakrabarti, Yang Guo, Qiuyun Chen, Qing Kenneth Wang
Abstract
is the causative gene at the 9p21 CAD susceptibility locus.
Topics & Concepts
Gene knockdownBiologyDownregulation and upregulationGene expressionGeneCell adhesionCancer researchMonocyteCoronary artery diseaseLong non-coding RNACell biologyMolecular biologyImmunologyCellGeneticsMedicineInternal medicineCancer-related molecular mechanisms researchRNA Research and SplicingRNA modifications and cancer