Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting
David M. Francis, Margaret P. Manspeaker, Paul A. Archer, Lauren F. Sestito, Alexander J. Heiler, Alex Schudel, Susan N. Thomas
Topics & Concepts
ImmunotherapyCancer researchImmune checkpointCancer immunotherapyImmune systemMonoclonal antibodyIn vivoSystemic administrationAntibodyAntibody-drug conjugateMedicineDrug deliveryPharmacologyImmunologyMaterials scienceBiologyNanotechnologyBiotechnologyCancer Immunotherapy and BiomarkersCancer, Stress, Anesthesia, and Immune ResponseImmunotherapy and Immune Responses