Rhodium-catalyzed transformations of diazo compounds <i>via</i> a carbene-based strategy: recent advances
Fatemeh Doraghi, Parsa Baghershahi, Mehran Ghasemi, Mohammad Mahdavi, Ahmed Al‐Harrasi
Abstract
a rhodium carbene-based strategy. Many heterocyclic and carbocyclic compounds, including isoquinolones and isocoumarins, quinoxalines, indoles, pyrrones, benzothazines, enaminones, benzenes and seven-membered rings, can be constructed using this rhodium-catalyzed system. The reaction mechanism involves C-H activation, carbene insertion and an annulation/functionalization sequence. This review describes the progress made in the last five years in rhodium-catalyzed transformations of diazo compounds as easily accessible precursors in organic chemistry.
Topics & Concepts
CarbeneDiazoRhodiumCatalysisAnnulationSurface modificationChemistryCombinatorial chemistryOrganic chemistryPhysical chemistryCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions