Identification of chymotrypsin-like protease inhibitors of SARS-CoV-2 <i>via</i> integrated computational approach
Salman Ali Khan, Komal Zia, Sajda Ashraf, Reaz Uddin, Zaheer Ul‐Haq
Abstract
) of Coronavirus. Considering the severity of the spread of coronavirus, the current study is in-line with the concept of finding the new inhibitors against the vital pathway of the corona virus to expedite the process of drug discovery.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
ProteaseDarunavirCoronavirusDrug developmentVirologyDrug repositioningComputational biologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DrugChemistryBiologyCoronavirus disease 2019 (COVID-19)VirusPharmacologyMedicineEnzymeBiochemistryViral loadInfectious disease (medical specialty)DiseaseAntiretroviral therapyPathologyComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Researchthermodynamics and calorimetric analyses