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Diverse chemical space of indoleamine-2,3-dioxygenase 1 (Ido1) inhibitors

Rahul Singh, Deepak B. Salunke

2020European Journal of Medicinal Chemistry27 citationsDOIOpen Access PDF

Topics & Concepts

Indoleamine 2,3-dioxygenaseChemistryKynurenineEnzymeKynurenine pathwayChemical spaceDrug discoveryImmune systemActive siteStructure–activity relationshipCofactorBiochemistryComputational biologyStereochemistryIn vitroTryptophanBiologyImmunologyAmino acidTryptophan and brain disordersBipolar Disorder and TreatmentStress Responses and Cortisol
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