Litcius/Paper detail

The potential role of resveratrol as supportive antiviral in treating conditions such as COVID-19 – A formulator’s perspective

Roy van Brummelen, Anna C. van Brummelen

2022Biomedicine & Pharmacotherapy37 citationsDOIOpen Access PDF

Abstract

With an increased transmissibility but milder form of disease of the omicron variant of COVID-19 and the newer antivirals often still out of reach of many populations, a refocus of the current treatment regimens is required. Safe, affordable, and available adjuvant treatments should also be considered and known drugs and substances need to be repurposed and tested. Resveratrol, a well-known antioxidant of natural origin, shown to act as an antiviral as well as playing a role in immune stimulation, down regulation of the pro-inflammatory cytokine release and reducing lung injury by reducing oxidative stress, is such an option. New initiatives and collaborations will however need to be found to unleash resveratrol's full potential in the pharmaceutical market.

Topics & Concepts

ResveratrolCoronavirus disease 2019 (COVID-19)Oxidative stressImmune systemPharmacologyAdjuvantDiseaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineImmunologyInfectious disease (medical specialty)EndocrinologyPathologySirtuins and Resveratrol in MedicinePARP inhibition in cancer therapyCOVID-19 Clinical Research Studies