Selective synthesis of pyridazine-fused chromones and 3-pyridazinyl chromones through intermolecular chromone annulation of <i>o</i>-hydroxyphenylenaminones with aryldiazonium salts
Siyu Song, Zhilai Zhang, Menglin Peng, Xueshan Xia, Shuwei Dong, Yongchao Wang, Fuchao Yu
Abstract
A chemodivergent and skeleton-controllable annulation reactions of readily available o -HPEs and aryldiazonium salts was described for the synthesis of highly functionalized pyridazine-fused chromones with high antiviral activity and higher safety.
Topics & Concepts
ChromoneChemistryAnnulationIntermolecular forceOrganic chemistryCombinatorial chemistryMoleculeCatalysisSynthesis of Organic CompoundsSynthesis and Reactivity of HeterocyclesSynthesis and Characterization of Heterocyclic Compounds